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Conformational Coupling of the Nucleotide-Binding and the Transmembrane Domains in ABC Transporters

Basic architecture of ABC transporters includes two transmembrane domains (TMDs) and two nucleotide-binding domains (NBDs). Although the transport process takes place in the TMDs, which provide the substrate translocation pathway across the cell membrane and control its accessibility between the two...

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Detalles Bibliográficos
Main Authors: Wen, Po-Chao, Tajkhorshid, Emad
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145290/
https://ncbi.nlm.nih.gov/pubmed/21806936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.06.031
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