Učitavanje...

Conformational changes of the nucleotide binding domains of P-glycoprotein induced by ATP hydrolysis

P-glycoprotein (Pgp) is a member of the ABC transporter superfamily with high physiological importance. Pgp nucleotide binding domains (NBDs) drive the transport cycle through ATP binding and hydrolysis. We use molecular dynamics simulations to investigate the ATP hydrolysis-induced conformational c...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:FEBS Lett
Glavni autori: Dehghani-Ghahnaviyeh, Sepehr, Kapoor, Karan, Tajkhorshid, Emad
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987826/
https://ncbi.nlm.nih.gov/pubmed/33159693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13992
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!