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Probing Cholesterol Binding and Translocation in P-glycoprotein
P-glycoprotein (Pgp) is a biomedically important member of the ABC transporter superfamily that mediates multidrug resistance in various cancer types. Substrate binding and transport in Pgp are modulated by the presence of cholesterol in the membrane. Structural information on cholesterol binding si...
में बचाया:
| में प्रकाशित: | Biochim Biophys Acta Biomembr |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934093/ https://ncbi.nlm.nih.gov/pubmed/31676371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2019.183090 |
| टैग : |
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