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Nucleotide-Dependent Conformational Changes in HisP: Molecular Dynamics Simulations of an ABC Transporter Nucleotide-Binding Domain

ATP-binding cassette (ABC) transporters mediate the movement of molecules across cell membranes in both prokaryotes and eukaryotes. In ABC transporters, solute translocation occurs after ATP is either bound or hydrolyzed at the intracellular nucleotide-binding domains (NBDs). Molecular dynamics (MD)...

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Detalhes bibliográficos
Main Authors: Campbell, Jeff D., Deol, Sundeep Singh, Ashcroft, Frances M., Kerr, Ian D., Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304884/
https://ncbi.nlm.nih.gov/pubmed/15377525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046870
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