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The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms
The 46/1 JAK2 haplotype predisposes to V617F-positive myeloproliferative neoplasms, but the underlying mechanism is obscure. We analyzed essential thrombocythemia patients entered into the PT-1 studies and, as expected, found that 46/1 was overrepresented in V617F-positive cases (n = 404) versus con...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145114/ https://ncbi.nlm.nih.gov/pubmed/20304805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236448 |
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