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C-Terminus of Heat Shock Protein 70–Interacting Protein–Dependent GTP Cyclohydrolase I Degradation in Lambs with Increased Pulmonary Blood Flow

We showed that nitric oxide (NO) signaling is decreased in the pulmonary vasculature before the development of endothelial dysfunction in a lamb model of congenital heart disease and increased pulmonary blood flow (Shunt). The elucidation of the molecular mechanism by which this occurs was the purpo...

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Autores principales: Sun, Xutong, Fratz, Sohrab, Sharma, Shruti, Hou, Yali, Rafikov, Ruslan, Kumar, Sanjiv, Rehmani, Imran, Tian, Jing, Smith, Anita, Schreiber, Christian, Reiser, Judith, Naumann, Susanne, Haag, Sebastian, Hess, John, Catravas, John D., Patterson, Cam, Fineman, Jeffery R., Black, Stephen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145069/
https://ncbi.nlm.nih.gov/pubmed/20870896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0467OC
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