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Disruption of Endothelial Cell Mitochondrial Bioenergetics in Lambs with Increased Pulmonary Blood Flow

Aims: The mitochondrial dysfunction in our lamb model of congenital heart disease with increased pulmonary blood flow (PBF) (Shunt) is associated with disrupted carnitine metabolism. Our recent studies have also shown that asymmetric dimethylarginine (ADMA) levels are increased in Shunt lambs and AD...

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Bibliographic Details
Main Authors: Sun, Xutong, Sharma, Shruti, Fratz, Sohrab, Kumar, Sanjiv, Rafikov, Ruslan, Aggarwal, Saurabh, Rafikova, Olga, Lu, Qing, Burns, Tantiana, Dasarathy, Sridevi, Wright, Johnny, Schreiber, Christian, Radman, Monique, Fineman, Jeffrey R., Black, Stephen M.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619212/
https://ncbi.nlm.nih.gov/pubmed/23244702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4806
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