HIV-1 Nef Binds the DOCK2–ELMO1 Complex to Activate Rac and Inhibit Lymphocyte Chemotaxis

The infectious cycle of primate lentiviruses is intimately linked to interactions between cells of the immune system. Nef, a potent virulence factor, alters cellular environments to increase lentiviral replication in the host, yet the mechanisms underlying these effects have remained elusive. Since...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	PLoS Biol
Hauptverfasser:	Janardhan, Ajit, Swigut, Tomek, Hill, Brian, Myers, Michael P, Skowronski, Jacek
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	PLOS 2004
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14737186/ https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020006
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!