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Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination

Gemcitabine is a cytidine analogue used in the treatment of various solid tumors. Little is known about how gemcitabine and its metabolites are transported out of cells. We set out to study the efflux of gemcitabine and the possible consequences of that process in cancer cells. We observed the efflu...

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Détails bibliographiques
Auteurs principaux: Rudin, Dan, Li, Liang, Niu, Nifang, Kalari, Krishna R., Gilbert, Judith A., Ames, Matthew M., Wang, Liewei
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144579/
https://ncbi.nlm.nih.gov/pubmed/21804948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7609.1000107
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