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Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination

Gemcitabine is a cytidine analogue used in the treatment of various solid tumors. Little is known about how gemcitabine and its metabolites are transported out of cells. We set out to study the efflux of gemcitabine and the possible consequences of that process in cancer cells. We observed the efflu...

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Detalhes bibliográficos
Main Authors: Rudin, Dan, Li, Liang, Niu, Nifang, Kalari, Krishna R., Gilbert, Judith A., Ames, Matthew M., Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144579/
https://ncbi.nlm.nih.gov/pubmed/21804948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7609.1000107
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