PGE(2)-EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB

BACKGROUND AND PURPOSE: Cerebral aneurysm is a frequent cerebrovascular event and a major cause of fatal subarachnoid haemorrhage, but there is no medical treatment for this condition. Haemodynamic stress and, recently, chronic inflammation have been proposed as major causes of cerebral aneurysm. Ne...

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Detalles Bibliográficos
Autores principales: Aoki, T, Nishimura, M, Matsuoka, T, Yamamoto, K, Furuyashiki, T, Kataoka, H, Kitaoka, S, Ishibashi, R, Ishibazawa, A, Miyamoto, S, Morishita, R, Ando, J, Hashimoto, N, Nozaki, K, Narumiya, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2011
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144537/
https://ncbi.nlm.nih.gov/pubmed/21426319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01358.x
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