PGE(2)-EP(2) signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-κB

BACKGROUND AND PURPOSE: Cerebral aneurysm is a frequent cerebrovascular event and a major cause of fatal subarachnoid haemorrhage, but there is no medical treatment for this condition. Haemodynamic stress and, recently, chronic inflammation have been proposed as major causes of cerebral aneurysm. Ne...

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Detalhes bibliográficos
Main Authors: Aoki, T, Nishimura, M, Matsuoka, T, Yamamoto, K, Furuyashiki, T, Kataoka, H, Kitaoka, S, Ishibashi, R, Ishibazawa, A, Miyamoto, S, Morishita, R, Ando, J, Hashimoto, N, Nozaki, K, Narumiya, S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144537/
https://ncbi.nlm.nih.gov/pubmed/21426319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01358.x
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