The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases()

Uridine phosphorylase (UP), a key enzyme in the pyrimidine salvage pathway, catalyzes the reversible phosphorolysis of uridine or 2′-deoxyuridine to uracil and ribose 1-phosphate or 2′-deoxyribose 1-phosphate. This enzyme belongs to the nucleoside phosphorylase I superfamily whose members show diver...

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Hlavní autoři: Tran, Timothy H., Christoffersen, S., Allan, Paula W., Parker, William B., Piskur, Jure, Serra, I., Terreni, M., Ealick, Steven E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144492/
https://ncbi.nlm.nih.gov/pubmed/21707079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200707z
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