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Structural analyses reveal two distinct families of nucleoside phosphorylases.

The reversible phosphorolysis of purine and pyrimidine nucleosides is an important biochemical reaction in the salvage pathway, which provides an alternative to the de novo purine and pyrimidine biosynthetic pathways. Structural studies in our laboratory and by others have revealed that only two fol...

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Detalhes bibliográficos
Main Authors: Pugmire, Matthew J, Ealick, Steven E
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222293/
https://ncbi.nlm.nih.gov/pubmed/11743878
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