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APC/C(Cdh1)-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage
Targeted protein destruction of critical cellular regulators during the G1 phase of the cell cycle is achieved by anaphase-promoting complex/cyclosome(Cdh1) (APC/C(Cdh1)), a multisubunit E3 ubiquitin ligase. Cells lacking Cdh1 have been shown to accumulate deoxyribonucleic acid (DNA) damage, suggest...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3144416/ https://ncbi.nlm.nih.gov/pubmed/21768287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201101062 |
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