Deletion of Multispecific Organic Anion Transporter Oat1/Slc22a6 Protects against Mercury-induced Kidney Injury

The primary site of mercury-induced injury is the kidney due to uptake of the reactive Hg(2+)-conjugated organic anions in the proximal tubule. Here, we investigated the in vivo role of Oat1 (organic anion transporter 1; originally NKT (Lopez-Nieto, C. E., You, G., Bush, K. T., Barros, E. J., Beier,...

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Hlavní autoři: Torres, Adriana M., Dnyanmote, Ankur V., Bush, Kevin T., Wu, Wei, Nigam, Sanjay K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143602/
https://ncbi.nlm.nih.gov/pubmed/21652719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.249292
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