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Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways

Multispecific drug transporters of the solute carrier and ATP-binding cassette families are highly conserved through evolution, but their true physiologic role remains unclear. Analyses of the organic anion transporter 3 (OAT3; encoded by Slc22a8/Oat3, originally Roct) knockout mouse have confirmed...

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Detalhes bibliográficos
Main Authors: Wu, Wei, Jamshidi, Neema, Eraly, Satish A., Liu, Henry C., Bush, Kevin T., Palsson, Bernhard O., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781372/
https://ncbi.nlm.nih.gov/pubmed/23920220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.052647
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