Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

The heterogeneous and chaotic nature of osteosarcoma has confounded accurate molecular classification, prognosis, and prediction for this tumor. The occurrence of spontaneous osteosarcoma is largely confined to humans and dogs. While the clinical features are remarkably similar in both species, the...

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Autori principali: Scott, Milcah C., Sarver, Aaron L., Gavin, Katherine J., Thayanithy, Venugopal, Getzy, David M., Newman, Robert A., Cutter, Gary R., Lindblad-Toh, Kerstin, Kisseberth, William C., Hunter, Lawrence E., Subramanian, Subbaya, Breen, Matthew, Modiano, Jaime F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143255/
https://ncbi.nlm.nih.gov/pubmed/21621658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2011.05.008
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