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Minnelide reduces tumor burden in preclinical models of osteosarcoma

Osteosarcoma is the most common bone cancer in children and adolescents with a five-year survival rate of about 70%. In this study, we have evaluated the preclinical therapeutic efficacy of the novel synthetic drug, Minnelide, a prodrug of triptolide on osteosarcoma. Triptolide was effective in sign...

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書目詳細資料
發表在:Cancer Lett
Main Authors: Banerjee, Sulagna, Thayanithy, Venugopal, Sangwan, Veena, Mackenzie, Tiffany N., Saluja, Ashok K., Subramanian, Subbaya
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386634/
https://ncbi.nlm.nih.gov/pubmed/23499892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.050
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