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Minnelide reduces tumor burden in preclinical models of osteosarcoma
Osteosarcoma is the most common bone cancer in children and adolescents with a five-year survival rate of about 70%. In this study, we have evaluated the preclinical therapeutic efficacy of the novel synthetic drug, Minnelide, a prodrug of triptolide on osteosarcoma. Triptolide was effective in sign...
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Publicado no: | Cancer Lett |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386634/ https://ncbi.nlm.nih.gov/pubmed/23499892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.050 |
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