Treatment of murine lupus with cDNA encoding IFN-γR/Fc

IFN-γ, a pleiotropic cytokine, is a key effector molecule in the pathogenesis of several autoimmune diseases, including lupus. Importantly, deletion of IFN-γ or IFN-γR in several lupus-predisposed mouse strains resulted in significant disease reduction, suggesting the potential for therapeutic inter...

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發表在:	J Clin Invest
Principais autores:	Lawson, Brian R., Prud’homme, Gerald J., Chang, Yigang, Gardner, Humphrey A., Kuan, Jason, Kono, Dwight H., Theofilopoulos, Argyrios N.
格式:	Artigo
語言:	Inglês
出版:	American Society for Clinical Investigation 2000
主題:	Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10903336/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10167
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