IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?
Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months of age, most female transgenics develop a lupus-like syndrome characterised by production of IgG anti-dsDNA, antihistone and antinucleo...
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| Publicado no: | Arthritis Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128871/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094455/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar124 |
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