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IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?
Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months of age, most female transgenics develop a lupus-like syndrome characterised by production of IgG anti-dsDNA, antihistone and antinucleo...
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2000
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC128871/ https://ncbi.nlm.nih.gov/pubmed/11094455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar124 |
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