PD-1 blockade by CT-011, anti PD-1 antibody, enhances ex-vivo T cell responses to autologous dendritic/myeloma fusion vaccine

We have developed a cancer vaccine in which autologous tumor is fused with dendritic cells (DCs) resulting in the presentation of tumor antigens in the context of DC mediated costimulation. In clinical trials, immunologic responses have been observed, however responses may be muted by inhibitory pat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rosenblatt, Jacalyn, Glotzbecker, Brett, Mills, Heidi, Vasir, Baldev, Tzachanis, Dimitrios, Levine, James D., Joyce, Robin M., Wellenstein, Kerry, Keefe, Whitney, Schickler, Michael, Rotem-Yehudar, Rinat, Kufe, Donald, Avigan, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142955/
https://ncbi.nlm.nih.gov/pubmed/21577144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31821ca6ce
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados