The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody

T-cell expression of programmed death receptor-1 (PD-1) down-regulates the immune response against malignancy by interacting with cognate ligands (eg, PD-L1) on tumor cells; however, little is known regarding PD-1 and natural killer (NK) cells. NK cells exert cytotoxicity against multiple myeloma (M...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Główni autorzy: Benson, Don M., Bakan, Courtney E., Mishra, Anjali, Hofmeister, Craig C., Efebera, Yvonne, Becknell, Brian, Baiocchi, Robert A., Zhang, Jianying, Yu, Jianhua, Smith, Megan K., Greenfield, Carli N., Porcu, Pierluigi, Devine, Steven M., Rotem-Yehudar, Rinat, Lozanski, Gerard, Byrd, John C., Caligiuri, Michael A.
Format: Artigo
Język:Inglês
Wydane: American Society of Hematology 2010
Hasła przedmiotowe:
Immunobiology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490105/
https://ncbi.nlm.nih.gov/pubmed/20460501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-271874
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy