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Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and tumor metastasis. The Notch intercellular signaling pathway regulates cell fate determination throughout metazoan evolution, and overexpression of activating alleles is oncogenic in mammals. Here we demonstrate that...

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Kaydedildi:
Yayımlandı:Genes Dev
Asıl Yazarlar: Timmerman, Luika A., Grego-Bessa, Joaquín, Raya, Angel, Bertrán, Esther, Pérez-Pomares, José María, Díez, Juan, Aranda, Sergi, Palomo, Sergio, McCormick, Frank, Izpisúa-Belmonte, Juan Carlos, de la Pompa, José Luis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2004
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701881/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.276304
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