Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and tumor metastasis. The Notch intercellular signaling pathway regulates cell fate determination throughout metazoan evolution, and overexpression of activating alleles is oncogenic in mammals. Here we demonstrate that...

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Bibliographic Details
Main Authors: Timmerman, Luika A., Grego-Bessa, Joaquín, Raya, Angel, Bertrán, Esther, Pérez-Pomares, José María, Díez, Juan, Aranda, Sergi, Palomo, Sergio, McCormick, Frank, Izpisúa-Belmonte, Juan Carlos, de la Pompa, José Luis
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
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Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC314285/
https://ncbi.nlm.nih.gov/pubmed/14701881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276304
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