Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and tumor metastasis. The Notch intercellular signaling pathway regulates cell fate determination throughout metazoan evolution, and overexpression of activating alleles is oncogenic in mammals. Here we demonstrate that...

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Bibliografische gegevens
Hoofdauteurs: Timmerman, Luika A., Grego-Bessa, Joaquín, Raya, Angel, Bertrán, Esther, Pérez-Pomares, José María, Díez, Juan, Aranda, Sergi, Palomo, Sergio, McCormick, Frank, Izpisúa-Belmonte, Juan Carlos, de la Pompa, José Luis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2004
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Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC314285/
https://ncbi.nlm.nih.gov/pubmed/14701881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276304
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