Notch signaling regulates left–right asymmetry determination by inducing Nodal expression

Generation of left–right asymmetry is an integral part of the establishment of the vertebrate body plan. Here we show that the Notch signaling pathway plays a primary role in the establishment of left–right asymmetry in mice by directly regulating expression of the Nodal gene. Embryos mutant for the...

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Bibliografische gegevens
Hoofdauteurs: Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, Saijoh, Yukio, O'Brien, Timothy P., Hamada, Hiroshi, Gridley, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2003
Onderwerpen:
Research Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196059/
https://ncbi.nlm.nih.gov/pubmed/12730124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1084703
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