Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and tumor metastasis. The Notch intercellular signaling pathway regulates cell fate determination throughout metazoan evolution, and overexpression of activating alleles is oncogenic in mammals. Here we demonstrate that...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Timmerman, Luika A., Grego-Bessa, Joaquín, Raya, Angel, Bertrán, Esther, Pérez-Pomares, José María, Díez, Juan, Aranda, Sergi, Palomo, Sergio, McCormick, Frank, Izpisúa-Belmonte, Juan Carlos, de la Pompa, José Luis
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2004
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC314285/
https://ncbi.nlm.nih.gov/pubmed/14701881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276304
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