Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

Epithelial-to-mesenchymal transition (EMT) is fundamental to both embryogenesis and tumor metastasis. The Notch intercellular signaling pathway regulates cell fate determination throughout metazoan evolution, and overexpression of activating alleles is oncogenic in mammals. Here we demonstrate that...

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Autori principali: Timmerman, Luika A., Grego-Bessa, Joaquín, Raya, Angel, Bertrán, Esther, Pérez-Pomares, José María, Díez, Juan, Aranda, Sergi, Palomo, Sergio, McCormick, Frank, Izpisúa-Belmonte, Juan Carlos, de la Pompa, José Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC314285/
https://ncbi.nlm.nih.gov/pubmed/14701881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276304
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