Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome

INTRODUCTION: Genetic heterogeneity likely contributes to variability in the symptoms among individuals with fragile X syndrome (FXS). Studies in the Fmr1 knockout (KO) mouse model for FXS suggest that excessive signaling through group I metabotropic glutamate receptors (Gp1 mGluRs), comprised of su...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thomas, Alexia M., Bui, Nghiem, Graham, Deanna, Perkins, Jennifer R., Yuva-Paylor, Lisa A., Paylor, Richard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142659/
https://ncbi.nlm.nih.gov/pubmed/21571007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2011.04.049
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