4-Vinylcyclohexene Diepoxide (VCD) Inhibits Mammary Epithelial Differentiation and Induces Fibroadenoma Formation in Female Sprague Dawley Rats

4-Vinylcyclohexene diepoxide (VCD), an occupational chemical that targets ovarian follicles and accelerates ovarian failure in rodents, was used to test the effect of early-onset reproductive senescence on mammary fibroadenoma formation. One-month female Sprague Dawley rats were dosed with VCD (80 m...

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Autori principali: Wright, Laura E., Frye, Jennifer B., Lukefahr, Ashley L., Marion, Samuel L., Hoyer, Patricia B., Besselsen, David G., Funk, Janet L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142287/
https://ncbi.nlm.nih.gov/pubmed/21621605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2011.05.005
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