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4-Vinylcyclohexene Diepoxide: A Model Chemical for Ovotoxicity

The occupational chemical 4-vinylcyclohexene diepoxide (VCD) has been shown to cause selective destruction of ovarian small pre-antral (primordial and primary) follicles in rats and mice by accelerating the natural, apoptotic process of atresia. Chemicals that destroy primordial follicles are of con...

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Autors principals: Kappeler, Connie J., Hoyer, Patricia B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307534/
https://ncbi.nlm.nih.gov/pubmed/22239082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/19396368.2011.648820
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