The Role of Hypoxia-Inducible Factor-1α in Acetaminophen Hepatotoxicity

Hypoxia-inducible factor-1α (HIF-1α) is a critical transcription factor that controls oxygen homeostasis in response to hypoxia, inflammation, and oxidative stress. HIF has been implicated in the pathogenesis of liver injury in which these events play a role, including acetaminophen (APAP) overdose,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sparkenbaugh, Erica M., Saini, Yogesh, Greenwood, Krista K., LaPres, John J., Luyendyk, James P., Copple, Bryan L., Maddox, Jane F., Ganey, Patricia E., Roth, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141908/
https://ncbi.nlm.nih.gov/pubmed/21576378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.180521
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados