Neonatal epithelial hypoxia inducible factor-1α expression regulates the response of the lung to experimental asthma

Allergic airway disease is characterized by a T helper type 2 cell-mediated airway inflammation and airway hyperresponsiveness. Little is known about the role of hypoxia-mediated signaling in the progression of the disease. To address this knowledge gap, a mouse model was created in which doxycyclin...

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Main Authors: Greenwood, Krista K., Proper, Steven P., Saini, Yogesh, Bramble, Lori A., Jackson-Humbles, Daven N., Wagner, James G., Harkema, Jack R., LaPres, John J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
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Editorial Focus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311510/
https://ncbi.nlm.nih.gov/pubmed/22180657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00193.2011
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