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HIF1α Is Essential for Normal Intrauterine Differentiation of Alveolar Epithelium and Surfactant Production in the Newborn Lung of Mice

Neonatal respiratory distress syndrome (RDS) is mainly the result of perturbation in surfactant production and is a common complication seen in premature infants. Normal fetal lung development and alveolar cell differentiation is regulated by a network of transcription factors. Functional loss of an...

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Detalhes bibliográficos
Main Authors: Saini, Yogesh, Harkema, Jack R., LaPres, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586263/
https://ncbi.nlm.nih.gov/pubmed/18801745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805927200
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