Identification of the Factors That Govern the Ability of Therapeutic Antibodies to Provide Postchallenge Protection Against Botulinum Toxin: A Model for Assessing Postchallenge Efficacy of Medical Countermeasures against Agents of Bioterrorism and Biological Warfare

Therapeutic antibodies are one of the major classes of medical countermeasures that can provide protection against potential bioweapons such as botulinum toxin. Although a broad array of antibodies are being evaluated for their ability to neutralize the toxin, there is little information that define...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Al-Saleem, Fetweh H., Nasser, Zidoon, Olson, Rebecca M., Cao, Linsen, Simpson, Lance L.
التنسيق: Artigo
اللغة:Inglês
منشور في: The American Society for Pharmacology and Experimental Therapeutics 2011
الموضوعات:
Toxicology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141897/
https://ncbi.nlm.nih.gov/pubmed/21586604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.180653
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