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LOCALIZATION OF THE SITES AND CHARACTERIZATION OF THE MECHANISMS BY WHICH ANTI-LIGHT CHAIN ANTIBODIES NEUTRALIZE THE ACTIONS OF THE BOTULINUM HOLOTOXIN

The recombinant, catalytically active light chain of botulinum toxin type A was evaluated as a potential vaccine candidate. Previous studies have shown that the light chain can elicit protective immunity in vivo. [5], but the underlying basis for this observation was not determined. In the present s...

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Detalhes bibliográficos
Main Authors: Takahashi, Tsuyoshi, Joshi, Suresh G., Al-Saleem, Fetweh, Ancharski, Denise, Singh, Ajay, Nasser, Zidoon, Simpson, Lance L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709450/
https://ncbi.nlm.nih.gov/pubmed/19428868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.02.051
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