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Neutralization of Botulinum Neurotoxin by a Human Monoclonal Antibody Specific for the Catalytic Light Chain

BACKGROUND: Botulinum neurotoxins (BoNT) are a family of category A select bioterror agents and the most potent biological toxins known. Cloned antibody therapeutics hold considerable promise as BoNT therapeutics, but the therapeutic utility of antibodies that bind the BoNT light chain domain (LC),...

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書誌詳細
主要な著者: Adekar, Sharad P., Takahashi, Tsuyoshi, Jones, R. Mark, Al-Saleem, Fetweh H., Ancharski, Denise M., Root, Michael J., Kapadnis, B. P., Simpson, Lance L., Dessain, Scott K.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515629/
https://ncbi.nlm.nih.gov/pubmed/18714390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003023
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