Evidence That Botulinum Toxin Receptors on Epithelial Cells and Neuronal Cells Are Not Identical: Implications for Development of a Non-Neurotropic Vaccine

Botulinum toxin typically interacts with two types of cells to cause the disease botulism. The toxin initially interacts with epithelial cells in the gut or airway to undergo binding, transcytosis, and delivery to the general circulation. The toxin then interacts with peripheral cholinergic nerve en...

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Detalhes bibliográficos
Main Authors: Elias, Md., al-Saleem, Fetweh, Ancharski, Denise M., Singh, Ajay, Nasser, Zidoon, Olson, Rebecca M., Simpson, Lance L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061530/
https://ncbi.nlm.nih.gov/pubmed/21106906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.175018
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