Sequence determinants of amyloid fibril formation
The establishment of rules that link sequence and amyloid feature is critical for our understanding of misfolding diseases. To this end, we have performed a saturation mutagenesis analysis on the de novo-designed amyloid peptide STVIIE (1). The positional scanning mutagenesis has revealed that there...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14691246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2634884100 |
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