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A deoxyribozyme that harnesses light to repair thymine dimers in DNA
In vitro selection was used to investigate whether nucleic acid enzymes are capable of catalyzing photochemical reactions. The reaction chosen was photoreactivation of thymine cyclobutane dimers in DNA by using serotonin as cofactor and light of wavelengths longer than the absorption spectrum of DNA...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314139/ https://ncbi.nlm.nih.gov/pubmed/14691255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305943101 |
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