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Sidechain Biology and the Immunogenicity of PDC-E2, the Major Autoantigen of Primary Biliary Cirrhosis
The E2 component of mitochondrial pyruvate dehydrogenase complex (PDC-E2) is the immunodominant autoantigen of primary biliary cirrhosis. Whereas lipoylation of PDC-E2 is essential for enzymatic activity and predominates under normal conditions, other biochemical systems exist that also target the l...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140764/ https://ncbi.nlm.nih.gov/pubmed/15558739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.20491 |
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