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Sidechain Biology and the Immunogenicity of PDC-E2, the Major Autoantigen of Primary Biliary Cirrhosis
The E2 component of mitochondrial pyruvate dehydrogenase complex (PDC-E2) is the immunodominant autoantigen of primary biliary cirrhosis. Whereas lipoylation of PDC-E2 is essential for enzymatic activity and predominates under normal conditions, other biochemical systems exist that also target the l...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2004
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140764/ https://ncbi.nlm.nih.gov/pubmed/15558739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.20491 |
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