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Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation

Radiation therapy remains a promising modality for curative treatment of localized prostate cancer, but dose-limiting toxicities significantly limit its effectiveness. Agents that enhance efficacy at lower radiation doses might have considerable value in increasing tumor control without compromising...

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Main Authors: Barreto-Andrade, Juan Camilo, Efimova, Elena V., Mauceri, Helena J., Beckett, Michael A., Sutton, Harold G., Darga, Thomas E., Vokes, Everett E., Posner, Mitchell C., Kron, Stephen J., Weichselbaum, Ralph R.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140695/
https://ncbi.nlm.nih.gov/pubmed/21571912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0061
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