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Over-expression of Ste20-related proline/alanine rich kinase (SPAK) exacerbates experimental colitis in mice
Inflammatory bowel disease (IBD), mainly Crohn’s disease (CD) and ulcerative colitis (UC), are characterized by epithelial barrier disruption and altered immune regulation. Colonic Ste20-like proline/alanine-rich kinase (SPAK) plays a role in intestinal inflammation, but its underlying mechanisms ne...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140558/ https://ncbi.nlm.nih.gov/pubmed/21705622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002910 |
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