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The PepT1–NOD2 Signaling Pathway Aggravates Induced Colitis in Mice

BACKGROUND & AIMS: The human di/tripeptide transporter hPepT1 is abnormally expressed in colons of patients with inflammatory bowel disease, although its exact role in pathogenesis is unclear. We investigated the contribution of PepT1 to intestinal inflammation in mouse models of colitis and the...

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Main Authors: Dalmasso, Guillaume, Nguyen, Hang Thi Thu, Ingersoll, Sarah A., Ayyadurai, Saravanan, Laroui, Hamed, Charania, Moiz A, Yan, Yutao, Sitaraman, Shanthi V, Merlin, Didier
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186842/
https://ncbi.nlm.nih.gov/pubmed/21762661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.080
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