The PepT1–NOD2 Signaling Pathway Aggravates Induced Colitis in Mice

BACKGROUND & AIMS: The human di/tripeptide transporter hPepT1 is abnormally expressed in colons of patients with inflammatory bowel disease, although its exact role in pathogenesis is unclear. We investigated the contribution of PepT1 to intestinal inflammation in mouse models of colitis and the...

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Auteurs principaux: Dalmasso, Guillaume, Nguyen, Hang Thi Thu, Ingersoll, Sarah A., Ayyadurai, Saravanan, Laroui, Hamed, Charania, Moiz A, Yan, Yutao, Sitaraman, Shanthi V, Merlin, Didier
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186842/
https://ncbi.nlm.nih.gov/pubmed/21762661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.080
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