PepT1 mediates transport of the proinflammatory bacterial tripeptide l-Ala-γ-d-Glu-meso-DAP in intestinal epithelial cells

PepT1 is a di/tripeptide transporter highly expressed in the small intestine, but poorly or not expressed in the colon. However, during chronic inflammation, such as inflammatory bowel disease, PepT1 expression is induced in the colon. Commensal bacteria that colonize the human colon produce a large...

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Detalhes bibliográficos
Main Authors: Dalmasso, Guillaume, Nguyen, Hang Thi Thu, Charrier-Hisamuddin, Laetitia, Yan, Yutao, Laroui, Hamed, Demoulin, Benjamin, Sitaraman, Shanthi V., Merlin, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950691/
https://ncbi.nlm.nih.gov/pubmed/20558765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00527.2009
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