Φορτώνει......
Perforin pores in the endosomal membrane trigger release of endocytosed granzyme B to the cytosol of target cells
How the pore-forming protein perforin delivers apoptosis-inducing granzymes to the cytosol of target cells is uncertain. Perforin induces a transient Ca(2+) flux in the target, which triggers a damaged cell membrane repair process. As a consequence, both perforin and granzymes are endocytosed into e...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140544/ https://ncbi.nlm.nih.gov/pubmed/21685908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2050 |
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