SYNTHESIS AND ANTIVIRAL EVALUATION OF 9-(S)-[3-ALKOXY-2-(PHOSPHONOMETHOXY)PROPYL]NUCLEOSIDE ALKOXYALKYL ESTERS: INHIBITORS OF HEPATITIS C VIRUS AND HIV-1 REPLICATION

We reported previously that octadecyloxyethyl 9-(S)-[3-hydroxy-2-(phosphonomethoxy)-propyl]adenine (ODE-(S)-HPMPA) was active against genotype 1b and 2a hepatitis C virus (HCV) replicons. This is surprising because acyclic nucleoside phosphonates have been regarded as having antiviral activity only...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Valiaeva, Nadejda, Wyles, David L., Schooley, Robert T., Hwu, Julia B., Beadle, James R., Prichard, Mark N., Hostetler, Karl Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139790/
https://ncbi.nlm.nih.gov/pubmed/21719300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.06.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados