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Triple isotopic labeling and kinetic isotope effects: Exposing H-transfer steps in enzymatic systems
Kinetic isotope effect (KIE) studies can provide insight into the mechanism and kinetics of specific chemical steps in complex catalytic cascades. Recent results from hydrogen KIE measurements have examined correlations between enzyme dynamics and catalytic function, leading to a surge of studies in...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139694/ https://ncbi.nlm.nih.gov/pubmed/21688781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2003873 |
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